Howie and Harlan are joined by Evangelos Oikonomou, a cardiologist and data scientist at the Yale School of Medicine, to discuss how AI can extract overlooked signs of heart disease from routine ECGs, imaging studies, and electronic health records—and how to deploy those tools responsibly at scale. Harlan explains whether a widely covered study suggesting that coffee may lower the risk of dementia should change your daily brew; Howie grapples with the ethical questions surrounding a proposed hepatitis B vaccine trial in Guinea-Bissau.
Show notes:
Coffee and Dementia
“Coffee and Tea Intake, Dementia Risk, and Cognitive Function”
“Coffee linked to slower brain ageing in study of 130,000 people”
“2 to 3 Cups of Coffee a Day May Reduce Dementia Risk. But Not if It’s Decaf.”
Evangelos Oikonomou
“What Is Opportunistic Screening in Healthcare?”
“Fellow Focus in Four: Evangelos Oikonomou, MD, DPhil, Cardiovascular Medicine”
Health & Veritas Episode 80: Josh Geballe: Turning Yale Innovation into Startups
“Are A.I. Tools Making Doctors Worse at Their Jobs?”
“The Robot Doctor Will See You Now”
Health & Veritas Episode 207: Robert Wachter: AI Is Already Remaking Healthcare
“A large language model for complex cardiology care”
Vaccine Trial Ethics
WHO: Statement on the planned hepatitis B birth dose vaccine trial in Guinea-Bissau
“Planned US-funded baby vaccine trial in Guinea-Bissau blasted by WHO”
“Guinea-Bissau suspends US-funded vaccine trial as African scientists question its motives”
“Guinea-Bissau Installs Military Ruler After Claims of a ‘Fabricated’ Coup”
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