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The University of Oxford in partnership with the Coler Lab at Seattle Children’s Research Institute (SCRI) has begun a new clinical trial called TB045, which aims to test tuberculosis (TB) vaccine safety and the host immune response in a first-in-man aerosol mycobacterial challenge infection model with healthy adult volunteers. TB is a disease caused by the bacterium Mycobacterium tuberculosis and in 2023 was the leading cause of death from an…

Former Conservative Prime Minister Theresa May, who can justifiably take the political credit for the passage of the UK’s ground-breaking  Modern Slavery Act 10 years ago today, famously described modern slavery as ‘the greatest human rights issue of our time.’Our experience of modern slavery research for policy teaches us that the patient and systematic resort to properly resourced, independent and expert policy-relevant research, evidence and data, which is the product…

Being an elephant is no easy task. As massive herbivores weighing several tons, they must consume vast amounts of low-calorie vegetation every day. However, their sheer size means that moving around to find food costs significant physical effort. Literally every step matters—especially in the vast, often harsh landscapes they traverse. African Elephant with GPS tracker. Image credit: Jane Wynyard, Save The Elephants. Understanding how elephants move through the landscape is…

The report finds that just ten universities are responsible for 53% of the UK’s spinouts, with Oxford securing the top position. Oxford’s success reflects its world-class research base, deep commercialisation expertise, and a strong network of investors and partners.This year’s report also highlights a significant reduction in the equity stakes taken by universities in spinouts. In 2024, the average university stake dropped to 16% – down from 22% the year…

These findings, published in the journal iScience, have important implications for understanding the technical abilities associated with the making of perishable tools – a topic which remains a highly unknown aspect of human technological evolution.Termites are a good source of energy, fat, vitamins, minerals and protein for chimpanzees. To eat the insects, chimpanzees need to use relatively thin probes to fish the termites out of the mounds where they live.…

In 2023, Tuberculosis (TB) caused more deaths worldwide than any other infectious disease. It is caused by the bacterium Mycobacterium tuberculosis, and although largely unheard of in the developed world by the late 20th century, cases have been rising globally in recent years and it continues to place an enormous social and economic burden on much of the developing world.Although often thought of as a lung disease, TB can infect…