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The DEN-HOST trial - a multi-site, placebo-controlled, randomised adaptive trial - is being delivered through a collaboration between the Pandemic Sciences Institute, the Programme for Research in Epidemic Preparedness and REsponse (PREPARE) under the Communicable Diseases Agency in Singapore, and the Oxford University Clinical Research Unit (OUCRU). It will initially involve trial sites in ten countries across Asia and Latin America, where dengue is endemic and represents a major public…

The University of Oxford has launched the world’s first Phase II clinical trial of a Nipah virus vaccine candidate.The trial, conducted in Bangladesh in partnership with the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), and funded by the Coalition for Epidemic Preparedness Innovations (CEPI), will assess the safety and immune response of the ChAdOx1 NipahB vaccine in a region where the virus causes recurrent outbreaks.The trial started earlier this…

Through a strategic collaboration with Microsoft, the AI assistant has been integrated into Microsoft Teams and will be piloted at Oxford University Hospitals (OUH) NHS Foundation Trust, marking one of the earliest deployments of 'agentic AI' within a clinically realistic tumour board setting.Multidisciplinary Tumour Board meetings (MDTs) are the gold standard for cancer treatment planning in the UK, convening radiologists, pathologists, surgeons, and oncologists to review diagnostic results and formulate…

Dr Tonya Lander. As the holidays approach, many of us will be buying chocolate as gifts for loved ones, but chocolate can no longer be relied on as an ‘affordable luxury.’ For the last 25 years, the price of cocoa was fairly stable, at around 2-3,000 GBP/metric ton. During the first half of 2024 and the start of 2025, however, the price quadrupled to over 8000 GBP/metric ton. Even though…

Dr Dan Challender. Photo credit: David Fisher. Overexploitation (harvesting at a rate that exceeds the ability of populations to recover) is a major driver of biodiversity loss. Globally, tens of thousands of animal, plant and fungi species are used and traded at different scales for purposes including food, fashion, medicine, pets, and building materials, among many others. Some of this use and trade is legal and sustainable and some not.…

The paper, 'The Levers of Political Persuasion with Conversational AI', published in Science, examines how large language models (LLMs) influence political attitudes through conversation.  Authored by a team from OII, AISI, the LSE, Stanford University and MIT, the research draws on nearly 77,000 UK participants and 91,000 AI dialogues, to provide the most comprehensive evidence to date on the mechanisms of AI persuasion and their implications for democracy and AI governance. Our results demonstrate the remarkable persuasive power of…

Neutrinos are one of the most mysterious particles in the universe, often called “ghost particles” because they rarely interact with anything else. Trillions stream through our bodies every second, yet leave no trace. They are produced during nuclear reactions, including those that take place in the core of our Sun. Their tendency to not interact often makes detecting neutrinos notoriously difficult.Capturing this interaction is an extraordinary achievement. Despite the rarity…

The University of Oxford and UBS are proud to announce the launch of the Oxford-UBS Centre for Applied Artificial Intelligence (AI). The Centre will aim to deepen the understanding of the power of AI through cutting-edge research and promote its practical application.   The Centre aims to be a ground-breaking interdisciplinary partnership involving UBS, the University of Oxford’s Saïd Business School and the University’s Mathematical, Physical and Life Sciences division (MPLS).…

Dr Alistair Farley. Credit: The IOI. On 10 December 1945, Alexander Fleming, Howard Florey, and Ernst Chain were jointly awarded the Nobel Prize in Physiology or Medicine ‘for the discovery of penicillin and its curative effect in various infectious diseases.’ The discovery of penicillin and its subsequent industrial production during World War Two is rightly hailed as one of the biggest medical breakthroughs of the 20th century. Penicillin played a…

Marking 75 years of the ECHR and 25 years since the Human Rights Act gave it effect in UK law, the research, ‘Examining 10 Reasons to Stay in the European Convention on Human Rights: Informing the Public Debate in the UK’, addresses a debate often dominated by claims about immigration control and widespread misunderstandings of what the ECHR does. Our analysis shows that the ECHR underpins everyday protections from digital privacy…